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Geick A, Eichelbaum M, Burk O: Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin.

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Currently WHO urges that TB programs worldwide adopt the practice of directly observed therapy (DOT), in which a health care worker observes each patient swallowing each dose of medicine.

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However, the trial patients are likely to be more acutely unwell than patients with tuberculosis and may require closer monitoring; additional tests may be requested at any time where necessary for patient management.

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